KMID : 1145120160140040473
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Asian Journal of Beauty and Cosmetology 2016 Volume.14 No. 4 p.473 ~ p.479
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Progress on Pathogenesis of Melanosis
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Yue Li-Zhi
Deng Xiao-Feng Li Li Meng Hong
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Abstract
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Melanosis is a common clinical pigmentation disorder which affects patients¡¯ facial aesthetics. This review describes the recent progress on mechanism of melanosis in order to provide the evidence for clinic therapy of melanosis. By investigating the recent progress of melanosis, we summarize the mechanism of melanosis from two aspects: endogenous and exogenous factors. Endogenous factors include genetic factors, endocrine, lipid peroxidation, endothelial function, blood rheology, trace elements and so on. Exogenous factors include ultraviolet (UV), skin microecology, improper use of cosmetics and so on. The pathogenesis of chloasma is given priority to endogenous factors. In depth and comprehensive understanding of the pathogenesis of chloasma contribute to the more effective prevention and treatment of chloasma.
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KEYWORD
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Melanosis, Etiology, Pathogenesis, Endogenous factors, Exogenous factors
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